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class="breadcrumb-item"><a href="/jkpd">醫(yī)美健康</a></li> <li id="c4uiuyacac" class="breadcrumb-item active" aria-current="page"> 國產(chǎn)乙肝創(chuàng)新藥納入國家醫(yī)保百億用藥市場格局或?qū)⒅厮? </li> </ol> </nav> </div> <div id="c4uiuyacac" class="mb-3"> <div> <a href="http://m.wygang.cn/bfjd" title=""> <img src="http://m.wygang.cn/static/uploads/images/2024/12/21/173474911867662bbeebbb8.gif" class="w-100"> </a> </div> </div> <h2 class="news-title">國產(chǎn)乙肝創(chuàng)新藥納入國家醫(yī)保百億用藥市場格局或?qū)⒅厮?/h2> <p class="news-info text-muted small"> <span id="c4uiuyacac" class=" small"> <i></i> </span> <span>2021-12-09 20:44:48</span> <span id="c4uiuyacac" class="text-muted small ml-3"><i></i></span> <span id="c4uiuyacac" class=""> sunmedia</span> <span id="c4uiuyacac" class="text-muted small ml-3"><i></i></span> <span>1476</span> </p> <hr /> <div id="c4uiuyacac" class="row"> <div id="c4uiuyacac" class="col-md-8 pr-md-0"> <div id="c4uiuyacac" class="news-content"> <p style="text-indent: 2em; margin-bottom:20px;">12月3日，2021年國家醫(yī)保談判結(jié)果出爐，中國首款原創(chuàng)口服抗乙肝病毒創(chuàng)新藥艾米替諾福韋片成功納入醫(yī)保。作為新型第二代替諾福韋，艾米替諾福韋片進入醫(yī)?；?qū)⒅厮車鴥?nèi)乙肝市場格局。</p><p style="text-indent: 2em; margin-bottom:20px;">乙肝是我國發(fā)病率最高的傳染病，其所對應的潛力市場一向是國內(nèi)多家藥企的“必爭之地”。據(jù)估計，我國約有7000萬例HBV感染者，其中約2000~3000萬例需要抗病毒治療的慢乙肝患者，位居世界首位；近十年來，每年新報告感染者數(shù)量在100萬左右，占甲乙類傳染疾病的三分之一，乙型肝炎仍是我國面臨的最嚴重的公共衛(wèi)生問題之一。</p><p style="text-indent: 2em; margin-bottom:20px;">從乙肝藥物市場數(shù)據(jù)來看，據(jù)弗若斯特沙利文分析，2021年中國乙肝藥物市場規(guī)模將達到16億美元，隨著更多創(chuàng)新型藥物進入市場，2025年其規(guī)模有望達到23億美元。值得注意的是，乙肝藥物的需求和潛在市場遠不止這些。</p><p style="text-indent: 2em; margin-bottom:20px;">《慢性乙型肝炎防治指南(2019年版)》推薦使用強效低耐藥的藥物，例如丙酚替諾福韋(TAF)、恩替卡韋(ETV)、替諾福韋二吡呋酯(TDF)和聚乙二醇干擾素。其中，恩替卡韋(ETV)是我國公立醫(yī)院抗乙肝病毒藥物市場占有率最高的藥物，2017年達到67%。與此同時，隨著百時美施貴寶的恩替卡韋(ETV)和吉利徳的富馬酸替諾福韋酯(TDF)專利到期，我國各大藥企紛紛入局仿制ETV和TDF。</p><p style="text-indent: 2em; margin-bottom:20px;">慢性乙肝患者治療是一個長期的過程，為減輕乙肝患者用藥經(jīng)濟負擔，國家醫(yī)保局已在第一、第二批集采中將三款常用的乙肝抗病毒藥物納入，具體為恩替卡韋、替諾福韋二吡呋酯和阿德福韋酯。3大乙肝用藥以價換量，集采后雖然銷量迎來大幅增長，但市場規(guī)模也出現(xiàn)明顯的萎縮。</p><p style="text-indent: 2em; margin-bottom:20px;">隨著主流乙肝抗病毒藥物納入集采、丙酚替諾福韋專利懸崖的到來，新的乙肝創(chuàng)新藥有望成為乙肝用藥市場的接捧者。</p><p style="text-indent: 2em; margin-bottom:20px;">艾米替諾福韋片(商品名：恒沐)是翰森制藥自主研發(fā)的第五個創(chuàng)新藥，2021年6月22日在中國獲批上市，成為中國首個口服乙肝抗病毒創(chuàng)新藥，獲批僅5個月就順利進入醫(yī)保。</p><p style="text-indent: 2em; margin-bottom:20px;">與已上市的創(chuàng)新藥、仿制藥相比，翰森制藥的艾米替諾福韋片雖屬“后起之秀”，但憑借驕人的臨床數(shù)據(jù)，且此次以更優(yōu)的價格進入2021年醫(yī)保談判目錄，業(yè)內(nèi)人士稱，相信該藥能夠從進口新藥和國產(chǎn)仿制藥的重圍之中殺出一片天地，重塑百億乙肝用藥市場格局，并推動治療方案更新迭代。</p><p style="text-indent: 2em; margin-bottom:20px;">來源：中國網(wǎng)財經(jīng)</p> <p style="text-indent: 2em; margin-bottom: 20px;"> </p> <p style="text-indent: 2em; margin-bottom: 20px;"> </p> </div> <div id="c4uiuyacac" class="row mt-3 align-items-center"> <div id="c4uiuyacac" class="col"> </div> <div id="c4uiuyacac" class="col-auto"> 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